aging Tag

Microplastics could be Factor in the movement of osteoporosis cases around the world, according to recently published research. The study reveals that when these tiny plastic particles enter the body, they disrupted the functioning of bone marrow stem cells, which are essential for bone tissue maintenance and repair.

Through your life your bones are filled. Osteoporosis is a state in which this process goes wrong, with bone breakdown, it is surpassed at the speed on which it is replaced. It leads to bone weakening with time and becomes more likely to break. The conditions have many risk factors, gender, medications, diet, smoking and drinks, and knowledge are known and genetics affect that – with disease are slowly developing over time. Often people don’t realize they have a condition until they break the bone.

This new analysis, published in Osteoporosis International magazine, adds exposure to microplasties as a potential new risk factor. The survey was reviewed by 62 scientific articles that initiated various laboratory and animal tests on the possible effects of micro-nanoplastics on the bone. The analysis of laboratory experiments showed that the microplasty encourages the formation of osteoculation, cells that created stem cells in bone marrow in bone bones for the promotion of resorption, a process in which the body is pierced and eliminates the old or damaged bone.

The study also found that, in relation to bones, plastic particles may reduce cell sustainability, cause prematurely aging the apartment, modify the genes expression and start inflammatory answers. The combination of these effects creates an imbalance in which osteoclasti destroy more tissue bones than is regenerated, causing the bone structure accelerated.

When they are viewed on animal studies, researchers have discovered that the accumulation of microplastics in the body reduces the number of white blood cells – which is suggestively modifications in the bone marrow function. In addition, these studies of the animal suggested that the impact of microplastics on osteoculars can be associated with the deterioration of the bones of microstructure and the formation of irregular cell structures, increasing the risk of brittle bones, deformities and breaks.

“In this study, the harmful effects observed culminated, worrisome, in the interruption of skeletal animal growth,” said Coachor Rodrigo Bueno de Oliveira in the public statement. “The potential impact of microplastics on the bone is the subject of scientific studies and is not negligible.”

Oliveira, who is the Coordinator for the Laboratory for the Evaluation of Mineral and Bones in Nephrology at the State University in Brazil, is now working with its team to further prove in practice between exposure to microplasts and the decay of bones. This research will begin by assessing the effects of microplastic particles on the misery of rodent producers.

“Although osteoometabolic diseases are relatively well understood, there is a gap in our knowledge in terms of the influence of microplastal for the development of these diseases. There is a potential eco-friendly reception, for example, the increase in the projected bone fracture.

Microplastics and nanoplasties are small plastic fragments – some so small ones are invisible to naked eye – which are separated from everyday items when sunlight, wind, rain, seawater or abrasion degrades. The main difference between two lies in their size: a microplastic measure from 1 micrometer (one thousand millimeters) to 5 millimeters, while nanoplastics are less than 1 micrometers. These particles were discovered throughout the world in natural environments, as well as in the whole human body and in meat, leading and various agricultural products.

Studies have begun to show that this type of plastic contamination can damage health. Experts claim that this means that urgently need to be reduced by their use of plastic. Every year, more than 500 million tons of materials are produced around the world, but only 9 percent are recycled, with many remains spreading into the environment and degradation.

This story originally appeared Wired In Spanish And he was translated from Spanish.

Statistics no Feeling: After 65, most people will fight to visually focus on close-up facilities. You may have seen it among your friends and relatives or even gained it yourself, holding books, magazines, or phone further than your face to try to invest words and pictures in focus. Many of those who are affected begin to use reading glasses. But a new treatment can become available: eye drops.

This deterioration vision is called presbyopia. It is not a disease, but a natural, physiological change caused by aging loss of charming lenses on the front of the eye, which reduces the ability of the eye to change the curvature of the lens to focus. This fixing begins in the middle age and usually stabilizes about 65 years. For people with short-sightedness, or mistake to see distant items, at the beginning of Presbyopia can initially lead to an improved vision compensation for their existing condition. For those with further light or hyperopia, the effects of presbooks often represent earlier than in the rest of the population.

I live with a prespecoach can cause fatigue and headaches, and in rare cases a double vision, but it is generally not concern. But correcting can facilitate daily activities and help maintain good quality of life. Classical correction agents are reading glasses, although in some cases they are decided by the eye surgery – there are laser refractive surgery for rehearsal for reimbursement of lens flexibility. The latter often suggests when there is also some blurring in the lens (cataract).

But recently, researchers work on eye drops that, in different ways, depending on the active ingredient used, improve close to the focus. Two species were approved by the American food and medicine administration: one on the basis of a substance called Aceclidin, others on pilocarpine.

Pilocrapine is a star molecule, with multiple tests of new formulations in progress. It is a natural alkaloid that acts with parts of the nervous system, which has the effect, in the eyes of the Miosa – narrowing the diameter of the pupils – and the contraction of muscles that controls the shape of the lens. The two effects combined improve the elasticity of the objects and the ability to focus on nearby objects.

The recent trial in Argentina tested the fall of the pilocarpin eye in different concentrations (1 percent, 2 percent, 3 percent) in a combination of Diclofenac, a non-steroidal anti-inflammatory attack that calms the negative effects of pilocarpas such as irritation and discomfort. (FDA-approved piloca is concentrated in 1.25 percent.)

In a two-year retrospective study of 766 people, an average year 55 years old, researchers found that eye drops enabled most of patients to improve their vision. “Our most significant result showed quick and lasting improvements in sight for all three concentrations,” said the main researcher of Giovanna Benozza when he was research at 43. Congress of the European Society of Cataracts and Surgeon Refraction.