Autism is not a single condition and there is no cause, scientists conclude
New research from The University of Cambridge suggests that autism must not be understood as a homogeneous condition of a single cause. Scientists have discovered that people are diagnosed in early childhood often have a different genetic profile than those diagnosed later in life, spreading understanding how the condition is developing.
The study analyzed the behavior of the autistic nation during childhood and adolescence in the UK and Australia. He also assessed the genetic data of more than 45,000 patients with the situation from different cohorts in Europe and the United States.
By connecting genetic information to age in diagnostics, researchers have noticed that the profiles of those who were different early to the situation differed early from those who received confirmation in later phases. They found only mild overlap between the two groups, which indicates that biological mechanisms are associated with autism may differ from those associated with autism identified in adolescence or adult.
Analysis, posted last week in the magazine NatureThey showed that children were diagnosed six years ago more likely to have behavioral difficulties – such as social interaction problems – from early age. In contrast, those diagnosed after 10 years were more likely to experience social and behavior difficulties during adolescence. They also had a larger predisposition in mental health conditions, such as depression.
The study adds that the average genetic profile of those diagnosed later was closer to the ADHD and the conditions such as post-traumatic stress disorder than the “classical” autism identified in early childhood.
The study concludes that timing diagnosis is not fully randomly, but reflects the fundamental genetic differences that match the risk for other conditions in some cases.
“We first discovered that the autism was diagnosed even later,” said Varun Warrier, a researcher at the Psychiatry Department at the University of Cambridge and the paper guide, in the press statement. “The term” autism “probably describes more conditions.”
Trump Tylenol Directive could actually increase autism rates, researchers warn
For decades, Discussion around autism was foci for unreasoning, misinterpretation and bad science, ranging from a long discredited link between neurodelupmentary condition and vaccine, in recent gluten and avoiding ultra-processed foods can reverse autistic properties.
On Monday evening, this spectrum appeared in an oval office, such as President Donald Trump announced the new Push to study the causes of autism with claims that the common patient tylenol, otherwise known as acetaminophen, can cause a state. The FDA then announced that the medicine would be a slap with a warning label called “Possible Association”.
David Amaral, Professor and the Director of the UC Davis Institute, was among those who died as the president launched in diarrhicus about Tylenol, in several times the pregnant women not to take it, even for the treatment of the blower.
“We heard that the President says that women should flow,” Amaral says. “I’m really confiscated because we know that the past, especially the risk factor for autism. That’s why I worry that this will don’t take Tylenol to make the conversely they hope.”
Speculation that surrounds Tylenol stems from correlations drawn in some studies that agreed to the Association between the use of hospitals and neurodeval disorders. One such analysis was published last month. The problem says Renee Gardner, an epidemiologist on the Caroline Institute in Sweden, whether these studies often reach this conclusion because there are not enough for what statistics describe as “those who may affect those who can affect the relationship between them.
Specifically, Gardner points out that pregnant women who need to take Tylenol more likely to have pain, fever and prenatal infections, which are very risk factors for autism. More importantly, given the heritage of autism, many of the genetic variants make women more likely to reduce immunity and greater perception of pain, and therefore they use hospitals such as acetaminophens, are also connected to autism. Use against hospital, she says, red herring.
Last year, Gardner and other scientists published what is widely considered a scientific field as the most declaring investigation so far on the subject, the one who has done an account for confusing factors. Using health records with nearly 2.5 million children in Sweden, they reached the opposite conclusion to the President: Tylenol has nothing to do with autism. Another great study of more than 200,000 children in Japan was published earlier this month, also did not find a relationship.
Doctors are worried that Trump allegations will have harmful consequences. Michael APTOLOW, Pediatric Advisor for Neurodiciness and Explorer in Pediatric Neuros at the King College London, says it will fear that pregnant women will start using other painkillers with a less checked security profile.
Gardner is worried that it will also lead to self-crying among parents, Flashback until the 1950s and 60s, time when autism is wrongly attributed to emotionally cold “mothers of cold.” “They make parents of children with neurodeval conditions feel responsible,” she says. “Harks return to the wounds of the dark days of psychiatry.”